Research Bibliography

The State of Autoimmune Disease in America: June–November 2025

176
Total Sources
12
Major Categories
Jun-Nov
Time Period 2025

Epidemiology & Prevalence

[1]
Background on Autoimmune Diseases - NCBI
June 1, 2022 NIH Publication
https://www.ncbi.nlm.nih.gov/books/NBK605884/
[2]
Estimation of prevalence of autoimmune diseases in the United States
December 11, 2024 PMC Journal
https://pmc.ncbi.nlm.nih.gov/articles/PMC11827834/
[3]
New study calculates autoimmune disease prevalence in U.S.
January 5, 2025 Mayo Clinic News
https://newsnetwork.mayoclinic.org/discussion/new-study-calculates-autoimmune-disease-prevalence-in-u-s/
[7]
Autoimmune Disease Prevalence Hits 5% in US: New Research
February 19, 2025 GlobalRPH News
https://globalrph.com/2025/02/autoimmune-disease-prevalence-hits-5-in-us-new-research/
[8]
Estimation of prevalence of autoimmune diseases - PubMed
December 11, 2024 PubMed
https://pubmed.ncbi.nlm.nih.gov/39666393/
[11]
Prevalence of Autoimmune Diseases - Johns Hopkins Pathology
December 31, 1996 Academic Resource
https://pathology.jhu.edu/autoimmune/prevalence
[12]
Estimation of prevalence of autoimmune diseases - JCI
February 16, 2025 Journal of Clinical Investigation
https://www.jci.org/articles/view/178722/ga
[19]
The Rise of Autoimmune Diseases | Sjögren's Foundation
March 25, 2025 Foundation Blog
https://sjogrens.org/blog/2025/the-rise-of-autoimmune-diseases

Policy & NIH Strategic Plan

[6]
Sjögren's Foundation Celebrates Release of First-Ever NIH Strategic Plan
August 27, 2025 Foundation Press Release
https://sjogrens.org/news/2025/sjogrens-foundation-celebrates-release-of-first-ever-national-institutes-of-health
[10]
Building Momentum Toward A Common Vision for Autoimmune Disease Research
July 23, 2025 Celiac.org
https://celiac.org/2025/07/24/building-momentum-toward-a-vision-for-autoimmune-disease-research/
[24]
NIH-Wide Strategic Plan for Autoimmune Disease Research
August 12, 2025 Autoimmune Institute
https://www.autoimmuneinstitute.org/research_updates/nih-wide-strategic-plan-for-autoimmune-disease-research/
[29]
NIH to Launch Inaugural Strategic Plan for Autoimmune Disease Research
July 17, 2025 NIH Record
https://nihrecord.nih.gov/2025/07/18/nih-launch-inaugural-strategic-plan-autoimmune-disease-research
[52]
NIH Unveils Inaugural NIH-Wide Strategic Plan for Autoimmune Disease Research
September 8, 2025 NIH ORWH
http://orwh.od.nih.gov/in-the-spotlight/nih-unveils-inaugural-nih-wide-strategic-plan-for-autoimmune-disease-research

Revolutionary Treatments & Clinical Trials

[22]
Novartis ianalumab first drug to reduce disease activity in Sjögren's disease Phase III trials
October 28, 2025 Novartis Press Release
https://www.novartis.com/news/media-releases/novartis-ianalumab-first-drug-reduce-disease-activity-and-patient-burden-sjogrens-disease-phase-iii-trials
[26]
Clinical trials to study new use for CAR T-cell therapy
January 20, 2025 UChicago Medicine
https://www.uchicagomedicine.org/forefront/immunotherapy-articles/2025/january/car-t-cell-therapy-treating-autoimmune-diseases
[28]
Cabaletta Bio Presents Positive Clinical Data
October 26, 2025 Cabaletta Press Release
https://www.cabalettabio.com/news-media/press-releases/detail/137/cabaletta-bio-presents-positive-clinical-data-and
[30]
Novartis showcases significant immunology advancements in ACR Congress
October 24, 2025 Novartis News
https://www.novartis.com/news/media-releases/novartis-showcases-significant-immunology-advancements-acr-congress-new-data-complex-autoimmune-diseases
[32]
SetPoint Medical Receives FDA Approval for Novel Neuroimmune Modulation Therapy
June 30, 2025 SetPoint Medical
https://setpointmedical.com/setpoint-medical-receives-fda-approval-for-novel-neuroimmune-modulation-therapy-for-rheumatoid-arthritis/
[56]
Top Type 1 Diabetes Research Breakthroughs to Watch in 2025
September 28, 2025 Type1Strong
https://www.type1strong.org/blog-post/top-type-1-diabetes-research-breakthroughs-to-watch-in-2025
[62]
A Cure for Type 1 Diabetes May be Closer Than You Think
October 14, 2025 Scientific American
https://www.scientificamerican.com/article/a-cure-for-type-1-diabetes-may-be-closer-than-you-think/
[81]
Investigator Outlines Promising Preliminary Results for CAR-T Therapies in Pediatric Autoimmune Diseases
October 27, 2025 ACR Convergence Today
https://www.acrconvergencetoday.org/investigator-outlines-promising-preliminary-results-for-car-t-therapies-in-pediatric-autoimmune-diseases/
[105]
Novartis Presents New Data From Potential First Targeted Sjögren's Treatment
October 28, 2025 BioSpace
https://www.biospace.com/drug-development/novartis-presents-new-data-from-potential-first-targeted-sjogrens-treatment
[109]
Safety and Efficacy of Ianalumab in Patients With Sjögren's Disease
May 27, 2025 PubMed
https://pubmed.ncbi.nlm.nih.gov/39557617/

Digital Health & AI Innovation

[110]
Innovative Diagnostic Techniques for Detecting Autoimmune Diseases
August 14, 2025 Autoimmune Institute
https://www.autoimmuneinstitute.org/articles/innovative-diagnostic-techniques-for-detecting-autoimmune-diseases
[116]
Mount Sinai Study Finds Wearable Devices Can Detect and Predict IBD Flare-Ups
January 15, 2025 Mount Sinai
https://www.mountsinai.org/about/newsroom/2025/mount-sinai-study-finds-wearable-devices-can-detect-and-predict-inflammatory-bowel-disease-flare-ups
[119]
Can AI help diagnose autoimmune encephalitis?
August 11, 2025 Encephalitis Info
https://www.encephalitis.info/news/can-ai-help-diagnose-autoimmune-encephalitis/
[122]
AI in ANA Testing: A New Era in Autoimmune Diagnostics
October 6, 2025 Medipan
https://www.medipan.de/ai-assisted-interpretation-of-ana-a-german-pilot-study/
[125]
Predicting the progression of autoimmune disease with AI
January 7, 2025 Penn State Health News
https://pennstatehealthnews.org/2025/01/predicting-the-progression-of-autoimmune-disease-with-ai/
[126]
Advancing personalized diagnosis and treatment using deep learning
March 26, 2025 Frontiers in Medicine
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1545528/full
[128]
The Promise of Artificial Intelligence in Autoimmune Disease
April 13, 2025 Autoimmune Institute
https://www.autoimmuneinstitute.org/articles/the-promise-of-ai-in-autoimmune-disease-from-early-detection-to-personalized-care
[142]
Digital Health Innovations: Revolutionizing Autoimmune Disease Management
September 18, 2025 Family Medicine Austin
https://familymedicineaustin.com/digital-health-innovations-revolutionizing-autoimmune-disease-management/

Mental Health Comorbidity

[68]
Navigating Mental Health with an Autoimmune Disease
September 21, 2025 Harbor Mental Health
https://harbormentalhealth.com/2025/09/22/navigating-mental-health-with-an-autoimmune-disease/
[71]
Autoimmune disease linked to doubling in depression, anxiety, bipolar risks
June 24, 2025 BMJ Group
https://bmjgroup.com/autoimmune-disease-linked-to-doubling-in-depression-anxiety-bipolar-risks/
[74]
Autoimmune Diseases Increase Risk Of Mood Disorders
June 24, 2025 Powers Health
https://www.powershealth.org/about-us/newsroom/health-library/2025/06/25/autoimmune-diseases-increase-risk-of-mood-disorders
[77]
Managing Mental Health with an Autoimmune Disease
July 31, 2024 Autoimmune Institute
https://www.autoimmuneinstitute.org/articles/managing-mental-health-with-an-autoimmune-disease

Sleep Disruption & Stress

[155]
The Impact of Stress on Autoimmune Disorders: Type 1 Diabetes and Systemic Lupus
March 25, 2025 PMC
https://pmc.ncbi.nlm.nih.gov/articles/PMC12025346/
[156]
Insomnia increases the risk for specific autoimmune diseases
April 9, 2025 Frontiers in Network Physiology
https://www.frontiersin.org/journals/network-physiology/articles/10.3389/fnetp.2025.1499297/full
[159]
One day of sleep deprivation can alter your immune system
February 23, 2025 AAI News
https://news.aai.org/2025/02/24/one-day-sleep-deprivation-can-alter-immune-system/
[162]
Insomnia increases the risk for specific autoimmune diseases - PubMed
April 9, 2025 PubMed
https://pubmed.ncbi.nlm.nih.gov/40276126/
[158]
Stress Management Techniques for Autoimmune Disease Patients
August 27, 2025 Perryman Rheumatology
https://www.perrymanrheum.com/stress-management-techniques-autoimmune-disease/

Gut Microbiome Connection

[46]
The role of gut microbiota in autoimmune disease progression
May 15, 2025 Frontiers in Microbiomes
https://www.frontiersin.org/journals/microbiomes/articles/10.3389/frmbi.2025.1553243/full
[48]
Role of Gut Microbiota in the Development of Some Autoimmune Diseases
March 24, 2025 PubMed
https://pubmed.ncbi.nlm.nih.gov/40162082/
[51]
Autoimmune diseases exhibit shared alterations in the gut microbiota
February 29, 2024 Rheumatology (Oxford)
https://academic.oup.com/rheumatology/article/63/3/856/7226506
[54]
Study reveals how gut bacteria might trigger autoimmune diseases like lupus
February 4, 2025 Yale News
https://news.yale.edu/2025/02/05/study-reveals-how-gut-bacteria-might-trigger-autoimmune-diseases-lupus

Healthcare Economics & Access

[44]
Autoimmune Disease Impact Report
March 23, 2025 RheumNow
https://rheumnow.com/news/autoimmune-disease-impact-report
[49]
Estimating the U.S. Economic Burden of Autoimmune Diseases
March 9, 2025 ISPOR
https://www.ispor.org/heor-resources/presentations-database/presentation-cti/ispor-2025/poster-session-4/estimating-the-u-s-economic-burden-of-autoimmune-diseases-a-pilot-systematic-literature-review
[106]
F.D.A. Moves to Speed Approvals for Cheaper Copycat Drugs
October 29, 2025 New York Times
https://www.nytimes.com/2025/10/29/health/fda-drug-prices-biosimilars.html
[107]
FDA Moves to Accelerate Biosimilar Development and Lower Drug Costs
October 28, 2025 HHS Press Room
https://www.hhs.gov/press-room/fda-accelerates-biosimilar-development-and-lowers-drug-costs.html
[111]
The Expanding Role of Biosimilars in Autoimmune Diseases
June 11, 2025 US Pharmacist
https://www.uspharmacist.com/article/the-expanding-role-of-biosimilars-in-autoimmune-diseases
[146]
Important Medicare Part D Changes: What Autoimmune Patients Need to Know
November 11, 2024 Autoimmune Association
https://autoimmune.org/blog/important-medicare-part-d-changes-what-autoimmune-patients-need-to-know-this-enrollment-period/
[152]
New Scorecard Highlights Access Barriers Faced by People Living with Autoimmune
January 25, 2023 Autoimmune Association
https://autoimmune.org/blog/healthplanscorecard/

Health Disparities & Equity

[94]
Study Finds Disparities in Autoimmune Rheumatic Diseases
October 13, 2025 ACR
https://rheumatology.org/press-releases/acr-convergence-2025-sheds-light-on-disparities-age-related-trends-and-epidemiology-in-autoimmune-rheumatic-diseases
[97]
ACR Convergence 2025 Sheds Light on Disparities
October 25, 2025 RheumNow
https://rheumnow.com/news/acr-convergence-2025-sheds-light-disparities-age-related-trends-and-epidemiology-autoimmune
[15]
Women with common autoimmune diseases may face higher death rate from heart disease
May 5, 2025 American Heart Association
https://www.heart.org/en/news/2025/05/06/women-with-common-autoimmune-diseases-may-face-higher-death-rate-from-heart-disease-stroke-than-men

Long COVID & Autoimmunity

[67]
Long COVID: What People with Autoimmune Disease Need to Know
March 25, 2025 Autoimmune Institute
https://www.autoimmuneinstitute.org/long-covid-faq/
[70]
Long COVID Syndrome Prevalence in 2025 in an Integral Healthcare Consortium
August 25, 2025 PMC
https://pmc.ncbi.nlm.nih.gov/articles/PMC12474489/
[76]
Long COVID 2025: Symptoms, diagnosis, post-COVID treatments
October 22, 2025 AMA
https://www.ama-assn.org/public-health/infectious-diseases/long-covid-2025-symptoms-diagnosis-post-covid-treatments-and

Vaccine Safety Studies

[130]
Large Danish Study: No link between vaccines and autism or 49 other health conditions
July 14, 2025 Statens Serum Institut
https://en.ssi.dk/news/news/2025/large-danish-study-no-link-between-vaccines-and-autism-or-49-other-health-conditions
[136]
IDSA 2025 Guidelines on the Use of Vaccines for Immunocompromised Patients
October 16, 2025 IDSA
https://www.idsociety.org/practice-guideline/idsa-2025-guidelines-on-the-use-of-vaccines-for-the-prevention-of-seasonal-covid-19-influenza-and-rsv-infections-in-immunocompromised-patients/

Research Funding Opportunities

[166]
Autoimmune Disease Grants - Eshelman Innovation
August 3, 2025 Eshelman Innovation
https://eshelmaninnovation.org/therapeutics-accelerator/autoimmune-grants/
[169]
Yale's Colton Center for Autoimmunity Announces 2025 Awardees
August 17, 2025 Yale Ventures
https://ventures.yale.edu/news/yales-colton-center-autoimmunity-announces-2025-awardees-advancing-innovation-autoimmune
[172]
Grants - Arthritis National Research Foundation
April 7, 2025 CureArthritis.org
https://curearthritis.org/research-grants/
[174]
2025 Research Funding Opportunity - The Myositis Association
September 25, 2025 Myositis Association
https://www.myositis.org/research/research-funding-opportunities/

Additional Research Sources

[58]
The Nobel Prize in Physiology or Medicine 2025
October 6, 2025 Reddit Science
https://www.reddit.com/r/science/comments/1nzltrq/the_nobel_prize_in_physiology_or_medicine_2025/
[50]
Autoimmune disease: genetic susceptibility, environmental triggers and immune recalibration
August 6, 2025 Frontiers in Immunology
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1626082/full
[167]
High-dose Vitamin D supplementation for immune recalibration in autoimmune disease
August 11, 2025 Frontiers in Immunology
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1625769/full
[79]
Updated 2025 ACG clinical guideline for the management of Crohn's disease
September 16, 2025 ACG Evidence-Based Guidelines
https://gi.org/journals-publications/ebgi/zhai_dalal_sep2025/
[34]
Repair, Remyelination, and Progress: What's Driving MS Innovation in 2025
March 23, 2025 NeurologyLive
https://www.neurologylive.com/view/repair-remyelination-progress-what-driving-ms-innovation-2025-
[120]
Tailoring Autoimmune Treatment with Precision Medicine
September 24, 2025 Autoimmune Institute
https://www.autoimmuneinstitute.org/articles/tailoring-autoimmune-treatment-with-precision-medicine
[25]
These immune cells won Nobel fame — can they solve autoimmune disease?
October 6, 2025 Nature
https://www.nature.com/articles/d41586-025-03287-y
[131]
Exercise and Autoimmune Conditions
August 11, 2025 Pivotal Motion Physiotherapy
https://pivotalmotion.physio/exercise-and-autoimmune-conditions/
[132]
Pregnancy & Autoimmune Conditions: What Expectant Mothers Need to Know
April 20, 2025 HR Pregnancy
https://hrpregnancy.com/pregnancy-autoimmune-conditions/
[135]
Pregnancy Brings Unique Challenges for People with Autoimmune Diseases
October 14, 2025 CU Anschutz News
https://news.cuanschutz.edu/news-stories/pregnancy-brings-unique-challenges-for-people-with-autoimmune-diseases-but-with-early-planning-pregnancy-outcomes-can-be-greatly-improved